Supplemental Data Files

Supplemental Data Files

Files in this Data Supplement:

• Supplemental Figure - Supplementary Figure 1. Scatterplots for quantitative correlation of microarray comparisons. A, F-KO:F-WT comparison to F-KO:M-KO. Shown are log2 ratios for F-KO:F-WT (x-axis) and the corresponding F-KO:M-KO data (y-axis) plotted on a log-log scale for all genes (n=93) where both ratios meet the criteria set in the Materials and Methods. The two conditions are correlated (r = 0.841) and the best-fit line (y = 0.97x + 0.04), shown in solid, has a slope near 1 and an intercept near 0. The 95% prediction boundaries are shown as dashed lines. B, M-WT:F-WT comparison to F-KO:F-WT. Similar to graph A, shown are the genes (n=146) meeting the aforementioned criteria for the M-WT:F-WT (x-axis) and F-KO:F-WT (y-axis) average log2 ratios. C, M-WT:M-KO comparison to F-KO:M-KO. Shown are the responses of sex-specific genes in the wild-type that also meet the aforementioned criteria for the M-WT:M-KO (x-axis) and F-KO:M-KO (y-axis) ratios (n=278 genes).
• Supplemental Tables - Supplementary Table 1. Average expression ratios for all 2231 genes of interest. The average expression ratios for the four microarray conditions are listed along with assigned gene categories based on the Total Flagging Sum (TFS). MMT accession numbers are identification numbers assigned to probes that could not be linked to a specific GenBank accession number. Expression ratios shown are average values based on 3 independent microarrays, each carried out in duplicate (dye swap). Values shown in bold are significant by P-value. Group numbers are assigned based on TFS, according to Table 4. Groups containing fewer than 15 members are not assigned groups numbers. Supplementary Table 2. Summary of the gene families found within the 2231 genes of interest. Each gene family and related proteins were counted from the 2231 genes of interest if the search term was found within the descriptors and annotations available from GeneSpring and Rosetta Resolver. The specific members within each gene family are listed in Supplementary Tables 3-16. Supplementary Table 3. Genes of interest containing the word "glutathione" within the full set of descriptors for each gene. Supplementary Table 4. Genes of interest containing the word fragment "serine protease inh" within the full set of descriptors for each gene. Supplementary Table 5. Genes of interest containing the phrase "solute carrier" within the full set of descriptors for each gene. Supplementary Table 6. Genes of interest containing the phrase "bile acid" within the full set of descriptors for each gene. Supplementary Table 7. Genes of interest containing the word "androgen" within the full set of descriptors for each gene. Supplementary Table 8. Genes of interest containing the word "steroid" within the full set of descriptors for each gene. Supplementary Table 9. Genes of interest containing the word "olfactory" within the full set of descriptors for each gene. Supplementary Table 10. Genes of interest containing the word fragment "sulfotransf" within the full set of descriptors for each gene. Supplementary Table 11. Genes of interest containing the word fragment "udp" within the full set of descriptors for each gene. Supplementary Table 12. Genes of interest containing the word "fatty" or "lipid" within the full set of descriptors for each gene. Supplementary Table 13. Genes of interest containing the word fragment "cytokin" or "interleuk" within the full set of descriptors for each gene. Supplementary Table 14. Genes of interest containing the word "kinase" within the full set of descriptors for each gene. Supplementary Table 15. Genes of interest containing the word fragment "phosphatas" within the full set of descriptors for each gene. Supplementary Table 16. Genes of interest containing the word fragment "zinc" or "transcrip" or "nuclear" or "DNA" within the full set of descriptors for each gene.